List of experiments

Aspergillus niger medium type:

Five sources of nitrogen, six minerals, six enzyme inducers and one each of growth as well as product promotors were screened by Plackett-Burman design, consisting of a total of 20 experiments for the above 19 sources/categories of medium ingredients, for their effect on the production of alpha-galactosidase by Aspergillus niger MRSS 234 in solid state fermentation system.

Keywords: Plackett-Burman, Saturated, Screening

Biological process characterization:

A recently developed class of three-level designs-definitive screening designs was employed to select a quadratic model that describes the effect of six input process parameters, including protein concentration, formaldehyde-to-protein ratio, lysine concentration, reaction duration, pH, and reaction temperature, on a formylation protein-crosslinking reaction.

Keywords: Center Runs, DSD, Foldover

Ceramic strength:

Compressive strength measurements were conducted on 32 macroporous biphasic calcium phosphate (MBCP) samples to evaluate the influences and interactions of five synthesis factors: chemical composition, percentage of macropores, mean size of macropores, isostatic compaction pressure, and sintering temperature.

Keywords: Center Runs, Screening, Fractional Factorial

Laser Etching:

Average rank for the quality of ecthing on a small plastic plate, using a laser.

Keywords: Blocking, DSD, Foldover, Screening

Polyethylene film:

The simultaneous effects of a range of additives and associated interactions on meltprocessing stability, processing discoloration, and long-term stability of a blown film-grade metallocene LLDPE (mLLDPE) were investigated by using a two-level factorial experimental design. The experiment was ran in blocks, where each block is a separate day, and the nine runs within each block were performed sequentially. This example was taken from chapter 2 of the book “A Comprehensive Guide to Factorial Two-level Experimentation” (2009) by Robert Mee.

Keywords: Center Runs, Blocking, Full Factorial